Study Links Obesity And Pancreatic Cancer
A direct link between pancreatic cancer and obesity has been discovered by researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC).
The study, published in the Cancer Prevention Journal, looked at two groups of mice — one fed a normal diet and another group fattened by high-calorie, high-fat diets.
The mice in the latter group were fatter, had less healthy pancreases and a higher incidence of PanIN lesions, or pancreatic intraepithelial neoplasia lesions, which are a common precursor to pancreatic cancer.
"The development of these lesions in mice is very similar to what happens in humans. These lesions take a long time to develop into cancer, so there is enough time for cancer preventive strategies, such as changing to a lower fat, lower calorie diet, to have a positive effect," said Dr. Guido Eibl, the study's lead author.
The survival rate for pancreatic cancer is less than 14 percent