Antidepressants may have adverse effects on sugar metabolism, leading to diabetes, according to researchers at the University of Southampton. The findings, published in the journal Diabetes Care, highlight the connection between increased antidepressant use and increased diabetes.
The team looked at 22 previous studies on the connection between the two, finding that people on antidepressants were more likely to suffer from diabetes."Our research shows that when you take away all the classic risk factors of type 2 diabetes; weight gain, lifestyle etc, there is something about antidepressants that appears to be an independent risk factor," said lead author Dr. Katharine Barnard.
Co-author Richard Holt, professor in Diabetes and Endocrinology at Southampton, added:"While depression is an important clinical problem and antidepressants are effective treatments for this debilitating condition, clinicians need to be aware of the potential risk of diabetes, particularly when using antidepressants in higher doses or for longer duration."Antidepressants are the third most prescribed drug in the U.S